Comparison between 24 and 48 Hours Interval between Mifepristone and Misoprostol for Induction of Abortion

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چکیده

Provision of safe abortion to the full extent of the law is an important component of reproductive health services. The development of methods of inducing abortion by medical means has created alternative options to make abortion available to women in health-care settings. Ideally, any method of medical abortion should have an overall efficacy comparable to that of surgical method, i.e. a rate of complete abortion of more than 95% and an ongoing pregnancy rate of less than 1%. The combination of mifepristone and misoprostol is now a well-established method for medical abortion in many countries. It has been shown by various studies to be a safe and effective method for the termination of pregnancy.

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منابع مشابه

Different Time Schedules of Mifepristone and Misoprostol in Second Trimester Medical Abortion: A Comparative Study

Background & aim: Recently, the use of mifepristone followed by misoprostol after 36-48 h has been demonstrated to be an effective and safe method for the second trimester medical abortion. However, this regimen entails long total abortion time, and consequently increases the financial burden and anxiety in the patients. We hypothesize that one day interval would be also effective and can be us...

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Mifepristone-misoprostol dosing interval and effect on induction abortion times: a systematic review.

OBJECTIVE To examine the effect of the interval between mifepristone and misoprostol administration on induction time (first misoprostol dose to abortion), total procedure time (mifepristone administration to abortion), and safety and efficacy in second-trimester induction abortion (13-24 weeks). DATA SOURCES We searched MEDLINE (1966-2012), ClinicalTrials.gov, POPLINE, and the Cochrane Contr...

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Different Time Schedules of Mifepristone and Misoprostol in Second Trimester Medical Abortion: A Comparative Study

Article type: Original article Background & aim: Recently, the use of mifepristone followed by misoprostol after 36-48 h has been demonstrated to be an effective and safe method for the second trimester medical abortion. However, this regimen entails long total abortion time, and consequently increases the financial burden and anxiety in the patients. We hypothesize that one day interval would ...

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A randomized trial to compare two dosing intervals of misoprostol following mifepristone administration in second trimester medical abortion.

BACKGROUND The conventional timing of misoprostol administration after mifepristone for second trimester medical abortion is 36-48 h, but simultaneous administration, which may make the regimen more convenient, has not been studied. The objective of this randomized comparison study is to compare two intervals of administration of misoprostol after pretreatment with mifepristone for second trime...

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Mifepristone followed by misoprostol or oxytocin for second-trimester abortion: a randomized controlled trial.

OBJECTIVE To compare two methods for induction of second-trimester abortion after priming the cervix with mifepristone. METHODS This was a randomized prospective trial carried out between January 2009 and February 2012. The participants were healthy women between 14 and 24 weeks of gestation with missed miscarriage or need for termination of pregnancy. All participants received oral 200 mg mi...

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تاریخ انتشار 2017